Metabolomics Society Forum

Software => R => XCMS => Topic started by: benjie on September 20, 2012, 09:28:44 PM

Title: matchedFilter terminates too early on an EIC?
Post by: benjie on September 20, 2012, 09:28:44 PM
matchedFilter finds peaks in a EIC, with a max that is a parameter of the filter function. However, it looks like as soon as it hits one peak that fails the S/N threshold, it stops looking for more peaks in that EIC. This is in line 729 of xcmsRaw.R. Should it continue to look for other peaks, ignoring the current one? I've got a case where the highest one has low s/n, but there are other peaks in the EIC, at different RTs.

Thanks.
Title: Re: matchedFilter terminates too early on an EIC?
Post by: Ralf on October 08, 2012, 05:11:43 PM
Not sure what you mean here. It should pick up all the relevant peaks above the noise threshold.
Can you give an example ?