Re: How can I do the processing data? normalization?
Reply #8 –
First thing to do is ask yourself if you can explain why a sample is different.
Does the loadings give a hint? -->
If all variables are on one side you have systematic sensitivity/concentration issues.
Does sample analysis order help explain?
Is it a well defined group of variables that cause the difference? What are they? Could they be contaminants?
Would you expect that there could be large differences between biological samples (e.g. different humans) or should they be much more similar than between treatments (e.g. different types of wine)?