I wonder if anyone knows how to deal with the default peak integration in MS-Dial and if that can be changed somehow?
I hope that attached image clearly depictures the issues I have: integration of peak in samples (S1-S6) and QCs are nice and clear while in all other samples (like Solvent for example), huge area under very tiny peak is added to overall peak area. This is very obvious when you see chromatograms, but after everything is exported to Excel, it becomes quite a problem. Especially for small peaks.
What I do not understand, is what baseline is used to perform integration like this? Obviously, using zero as a baseline is not ideal in chromatography peaks, especially if baseline is drifting.
Any suggestions and any explanation/help are welcome!
By the way, I am using MS-Dial for couple of years and in my opinion it is the best Metabolomics/Lipidomics software I tried so far. Great thanks to the developers!