Metabolomics Society Forum

Software => MS-DIAL => Topic started by: msss on March 13, 2021, 01:14:43 AM

Title: The sigma window value in dec tab
Post by: msss on March 13, 2021, 01:14:43 AM
Hi Hiroshi,

I would like to know what is "sigma window value" and how to filter ms2 peak based on th sigma value? what's the meaning of
matchedFilterCoefficient in the souce code posted on the official website?
Code: [Select]
matchedFilterCoefficient[i] = (1 - Math.Pow((-halfPoint + i) / sigma, 2)) * Math.Exp(-0.5 * Math.Pow((-halfPoint + i) / sigma, 2))

Thanks in advance!

Best regards
yang
Title: Re: The sigma window value in dec tab
Post by: Hiroshi Tsugawa on March 13, 2021, 09:32:58 AM
Hi,

see the Supplementary Data 4 of the following article?
https://www.nature.com/articles/nmeth.3393#Sec16

Hiroshi
Title: Re: The sigma window value in dec tab
Post by: msss on March 15, 2021, 10:40:05 PM
thank you! It is very helpful
but how to reconstruct the link between precursor and fragment ions ? depend on rt?

Best regards
yang