Metabolomics Society Forum

Software => MS-DIAL => Topic started by: QizhiSu on June 07, 2022, 12:20:12 AM

Title: Peak area is about 24 times higher after simultaneously curate alignment
Post by: QizhiSu on June 07, 2022, 12:20:12 AM
Hi all,

Has anybody ever experienced substantial peak area change after manually curating peak alignment using the "Aligned chromatogram viewer for the simultaneous curation" function?
(http://D:\OneDrive - unizar.es\Escritorio\Snipaste_2022-06-07_08-09-14.png)

I just find it weird. For me, after manually curating, all peak areas are about 24 times larger.
(http://D:\Data process software\msdial_bug_report\20220607_peak_area_change_after_manually_alignment (Small).png)

Any idea about why this happens? And how to avoid this situation?

Best regards,
Qizhi Su