Metabolomics Society Forum

Software => R => XCMS => Topic started by: andrea.faccio on August 12, 2014, 04:54:03 PM

Title: Into or maxo
Post by: andrea.faccio on August 12, 2014, 04:54:03 PM
Why do people normally use  "into" (integrated intensity) instead of  "maxo" (maximum intensity) on the diffreport step? Is there a specific reason for that? Does anyone  have a reference about that?

Thank you
Title: Re: Into or maxo
Post by: hpbenton on August 15, 2014, 01:58:09 PM
andrea,

Maximum intensity corrosponds to the peak height. This value is know to be highly variable in a dataset for the same peak. However, peak area is a much more robust measurement. There are certain situations where peak height is desired however, mostly this is just to get the correct plotting parameters for the EIC's :)

Cheers,

Paul