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Topic: Outliers (Read 3144 times) previous topic - next topic

Outliers

Quick question: if I get an outlier sample, should I rerun all preprocessing steps in xcms (ie. group, retcor etc.)?

I'm using retcor with orbitrap and profstep=0.1 so the process is currently using the outlier sample as a center sample...suffice to say I'm wondering if that means retention time correction has to be repeated?

Thanks!

Re: Outliers

Reply #1
Depends why it is an outlier. RT shifts or just very different intensities? If the first it could make sense. If not then no I would say. If no shift but unique features pruning those features from the peaktable might be fine.
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