Data from waters - mass measure in centroid mode
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Dear all

We work with a synapt G2, Waters, drived with masslynx software. We work in profile mode currently and we apply the correction along the run.

When I convert my data with MS convert, and I check with insilico viewer the peak picking, I observe that the value is the value corresponding to the profile value in masslynx but not to the centroid value. This induces an error of 10 to 15 ppm compared to the exact mass value, instead of 2 to 5 ppm.

Do anyone have a solution to this problem? I checked the filter lockmass refiner but it didn't work (first filter lockmass refiner then filter peak picking with CWT algorithm).

Thanks