Issues with Lipidomics Mode [Crashing, will not run files that have ran before] April 13, 2020, 11:07:19 AM Good morning--Recently my lab has ran into an issue where MS-DIAL won't run negative mode files for lipidomics. I tried to run new files of E. coli and the negative mode files will either crash the program (it actually locked my computer up for ~30 minutes with just a black screen) or take several hours to run and then return zero ref matches. A coworker attempted to run files on their computer that had worked previously on both the latest version and an earlier version (4.00) and the program crashed within a few seconds each time but the same file in metabolomics ran as expected. Running the same file as metabolomics returns 4 matches. Is anyone else experiencing/experienced similar issues or have a fix?I am using ver4.18, data can be made available on request.