Taking into account the batch effect

March 05, 2021, 04:51:49 AM

Hi everyone,

I was wondering if I could ask you a question when you injected multiple samples in different batch. In the sample description it is possible to set different batch numbers for the files (and analytical order). Therefore I was wondering if MS-DIAL can account for the batch effect (described in this paper for example: https://doi.org/10.1021/ac302877x). Is it done in the LOESS regression? If so, could I have some information on how the data is normalized?

Thanks a lot
Jean

Re: Taking into account the batch effect

Reply #1 – March 13, 2021, 02:51:26 AM

Hi Jean

see this: https://mtbinfo-team.github.io/mtbinfo.github.io/MS-DIAL/tutorial.html#section-5-5

Hiroshi