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Topic: How to analyze Agilent 6560 ion mobility AIF data? (Read 480 times) previous topic - next topic

How to analyze Agilent 6560 ion mobility AIF data?

Hi,

I have a question about using MSDial to analyze the Agilent 6560 ion mobility AIF data. For example, in attached picture 1, when I select chromatography as the separation type, "SWATH-MS" and "All ion with multiple CES" option are available in the MS Method type.

However, in attached picture 2, when I select the "Ion mobility" in the separation type, there is no option about "all ion with multiple CES"

Thus, I am wondering how to use the MSDial to analyze the data which run under ion mobility and AIF using Agilent 6560.

Thanks a lot

 

Re: How to analyze Agilent 6560 ion mobility AIF data?

Reply #1
Hi.

I have been working with AIF IMS data and to analyse them through MS-DIAL you should check Ion mobility and then data independent MS/MS. In my view, so far MS-DIAL is not able to distinguish the different energy collisions in this system.

Hope it help you.

Should you have more questions, please send me an email:
acarolinarosa.16@gmail.com


Best Regards,
Ana Carolina

Re: How to analyze Agilent 6560 ion mobility AIF data?

Reply #2
Hi,

Ana is true. Sorry, at this moment, MS-DIAL cannot utilize the multiple CEs data at ion mobility project.

Hiroshi