S/N (signal-to-noise) filter in MS-DIAL November 16, 2022, 02:10:20 PM Hi all,I couldn't find an answer for this in this forum or generally online. MS-DIAL routinely calls peaks like those in the attached screenshot. The average S/N of these peaks is extremely low. I would like to avoid these peak calls altogether: is there a setting in MS-DIALs peak picking/featurization that would allow me to avoid these? If not, can I filter them out after peak-picking? Is there any place to set a threshold such that any feature with average SN below that threshold is not shown in the alignment?I can certainly export the data to python and do it there easily, but for quick GUI based processing I would love to be able to do this.Any advice greatly appreciated.Thanks,Will 1 Likes
Re: S/N (signal-to-noise) filter in MS-DIAL Reply #1 – November 17, 2022, 04:15:52 AM Quote from: wdwvt1 on November 16, 2022, 02:10:20 PMHi all,I couldn't find an answer for this in this forum or generally online. MS-DIAL routinely calls peaks like those in the attached screenshot. The average S/N of these peaks is extremely low. I would like to avoid these peak calls altogether: is there a setting in MS-DIALs peak picking/featurization that would allow me to avoid these? If not, can I filter them out after peak-picking? Is there any place to set a threshold such that any feature with average SN below that threshold is not shown in the alignment?I can certainly export the data to python and do it there easily, but for quick GUI based processing I would love to be able to do this.Any advice greatly appreciated.Thanks,WillHi Will,I suppose changing the amplitude under peak detection and MSDec tabs would get you the desired results? Does setting a higher cut-off not resolve this issue?Are these so called peaks above your set noise level? 1 Likes
Re: S/N (signal-to-noise) filter in MS-DIAL Reply #2 – November 28, 2022, 10:38:20 PM Yes, agreed, that a S/N filter in the "alignment table" during display of results in the GUI would help the analysis and visualization as well!
Topic: S/N (signal-to-noise) filter in MS-DIAL