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Topic: Question about Bruker QTOF raw data in MS-DIAL (Read 64 times) previous topic - next topic

Question about Bruker QTOF raw data in MS-DIAL

Hi there,
I am using MS-DIAL to process data coming from an older qTOF compact we have in our institution. We have encountered some issues with these data when converting to mzXML/mzML using msconvert, wherein the conversion incorrectly uses the uncalibrated precursor m/z in MS2 scans, which meant a lot of MS2 spectra ended up being unconnected to corresponding MS1 peaks.

I wonder, since MS-DIAL seems to read bruker .d natively, can we assume that this issue is handled correctly when processing the datafiles (assuming they are calibrated before processing)?

Best,
Silas