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Topic: Are MS files generated in append-only fashion? (Read 4492 times) previous topic - next topic

Are MS files generated in append-only fashion?

I asked the following question on the ProteoWizard's msconvert forum, and they (Parag Mallick, the top engineer) said that the XCMS engineers were working on it and I should ask them:
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Would anyone know if the main MS vendors (Thermo, Ab-Sciex, Agilent, Waters -- in that order) create their MS raw files as "append-only"? That is, the data always gets appended to the end as these files get generated by the MS? If they're not 100% append, are they mainly append, at least while the MS is generating the file?
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