Re: Consequences of using Centwave for profile mode data
Reply #1 –
Gusses of what will happen:
* She uses a wide mz window in peak picking to get the whole peak inside. In effect treating it like it has much less resolution
* She uses a normal mz window (ppm) and each peak is split in many pieces. Each real peak is represented by many features in her feature table. Probably there is many more features than you would expect.
It is hard to imagine you could do this without noticing. Perhaps they put the raw data up but forgot to say that they centroided?