In our lab, we are using WATERS QTOF. I recently found that the m/z values of the results from XCMS is off around 0.1-0.2 Da from those of Progenesis (software developed by WATERS). I believe the m/z values of Progenesis are right since those values agree with the raw data where I applied mass correction during data acquisition. I just wonder if anyone have similar problems before. Is there any parameters in XCMS related to mass correction? Any help will be appreciated.