benchmark ver 4.9.221218 vs 5.1.230222 March 23, 2023, 05:25:00 AM Hi, I processed an identical set of metabolomics data using identical parameters either in ver 4.9.221218 or ver 5.1.230222.MS-DIAL 4.9.221218 processed 164 files in 7 minutes (from the first "dcl" file to last) and saved the alignment file in next 6 minutes.Total 13 minutes.MS-DIAL 5.1.230222 processed 164 files in 20 minutes (from the first to the last) and I canceled the alignment after 60 minutes (CPU at constant ~6.6% and slowly increasing allocated memory ~14.2 GB).Total 20 + 60... Update, after fresh restart:MS-DIAL 5.1.230222 processed 164 files in 19 minutes (from the first to the last) and finished the alignment in 2 hours and 11 minutes. Total 2 h 20 min.O. Quote Selected Last Edit: March 23, 2023, 07:54:45 AM by Ondrej